Millie Bobby Brown

Enola Holmes

Paul Copley

Station Master

Ellie Haddington

Miss Gregory

Alex Kelly

Miss Gregory II

Dempsey Bovell

Fleet Street Hawker

Neil Bell

Constable

David Kirkbride

Agitator

Delroy Atkinson

Porter

Mary Roscoe

Grace Whitting

Owen Atlas

Young Sherlock Holmes (uncredited)

Pierre Bergman

Detective (uncredited)

Gianni Calchetti

Roy (uncredited)

Gaby French

Seamstress

Hattie Morahan

Lady Tewkesbury

Henry Cavill

Sherlock Holmes

Sam Claflin

Mycroft Holmes

Helena Bonham Carter

Eudoria Holmes

Louis Partridge

Lord Tewkesbury

Adeel Akhtar

Lestrade

Fiona Shaw

Miss Harrison