Antonio Banderas

Puss in Boots (voice)

Bob Joles

Giuseppe (voice)

Latifa Ouaou

Crazy Woman / Mean Girl / Milk Lady / Little Boy (voice)

Bob Persichetti

Ohhh Cat (voice)

Sergio Bruna

Soldier (voice) (uncredited)

Rebecca Davis

Various Cats (voice) (uncredited)

Jossara Jinaro

Additional Voices (voice) (uncredited)

Lara Jill Miller

Additional Voices (voice) (uncredited)

Joshua Rush

Additional Voices (voice) (uncredited)

Tom McGrath

Bar Thief (voice)

Chris Miller

Little Boy Blue / Friar Miller / Prison Guard / Manuel / Rafael (voice)

Salma Hayek

Kitty Softpaws (voice)

Zach Galifianakis

Humpty Dumpty (voice)

Billy Bob Thornton

Jack (voice)

Amy Sedaris

Jill (voice)

Constance Marie

Imelda (voice)

Mike Mitchell

Andy Beanstalk (voice)

Guillermo del Toro

Comandante / Hombre del bigote (voice)

Conrad Vernon

Raoul / Soldier (voice)

Julie Wittner

Various Cats (voice) (uncredited)