Tobey Maguire

Homer Wells

Charlize Theron

Candy Kendall

Michael Caine

Dr. Wilbur Larch

Delroy Lindo

Arthur Rose

Paul Rudd

Lt. Wally Worthington

Jane Alexander

Nurse Edna

Kathy Baker

Nurse Angela

Erykah Badu

Rose Rose

Kieran Culkin

Buster

Kate Nelligan

Olive Worthington

Heavy D

Peaches

J.K. Simmons

Ray Kendall

Erik Per Sullivan

Fuzzy

Paz de la Huerta

Mary Agnes

K. Todd Freeman

Muddy

Evan Parke

Jack

Jimmy Flynn

Vernon

Lonnie Farmer

Hero

Spencer Diamond

Curly

Skye McCole Bartusiak

Hazel