Pablo Schreiber

Master Chief / Spartan-117

Charlie Murphy

Makee

Kate Kennedy

Kai-125

Bentley Kalu

Vannak-134

Olive Gray

Dr. Miranda Keyes

Natasha Culzac

Riz-028

Shabana Azmi

Margaret Parangosky

Bokeem Woodbine

Soren-066

Jen Taylor

Cortana (voice)

Natascha McElhone

Dr. Catherine Halsey

Danny Sapani

Jacob Keyes