Melissa McCarthy

Tammy

Sarah Baker

Becky

Mia Rose Frampton

Karen

Steve Little

Jet Ski Rental Guy

Mark L. Young

Jesse

Oscar Gale

Javier

Zach Hanner

Man at Blue Post Bar-B-Que

Ricky Muse

Officer Curtis

William Flaman

La Grange Bail Cop

Ben Falcone

Keith

Nat Faxon

Greg

Susan Sarandon

Pearl

Kathy Bates

Lenore

Allison Janney

Deb

Dan Aykroyd

Don

Gary Cole

Earl

Sandra Oh

Susan

Mark Duplass

Bobby

Toni Collette

Missi

Rey Hernandez

Cop at Lakehouse